Uganda Prepares to Start Ebola Vaccine Trials as Minister Aceng, WHO, Make Final Assessments

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The World Health Organization (WHO) country representative Yonas Tegegn Woldemariam and Ugandan minister of Health Jane Ruth Aceng have made final assessments of the clinical trial base in Kampala, as the country prepares to start Ebola vaccine trials.

The two officials took stock of equipment that have been procured for use during the trial. Items toured included the cold chain, Personal Protective Equipment, study tablets for the research teams, and other medical materials.

Principal Investigator, Prof. Bruce Kirenga told the Press and the visiting teams that, “Preparedness is now at 92 per cent.”

Trial Manager Dr Joanita Nalunjogi said that five research teams have been recruited, and trained and are ready for deployment once the vaccines arrive in the country.

According to the WHO country representative Dr Tegegn, the team is looking at three candidate vaccines to use in the trial period including the CAD3 Sabin vaccine, CADOX1 from the University of Oxford and the rsvs the Merck/IAVI Vaccine to test whether one or more will protect against Ebola caused by the Sudan ebola virus.

Health Minister Aceng pointed out that Uganda is doing ground-breaking work that will have uses far beyond the current outbreak.

“We shall be providing science to the whole world when all this is done,” Aceng said.

Aceng highlighted the importance of the research teams following the research protocol that she said that has now received necessary approvals from ethics and other regulatory committees.

She commended the strong leadership of the Principal Investigator, Prof Kirenga.

According to the data from the Ministry of Health, at least 141 confirmed cases of Ebola have been recorded and 22 probable cases (a total of 163 cases). There are 55 confirmed deaths and 22 probable deaths (a total of 77 deaths).

The data also shows that there are 544 active contacts listed in five districts.
Altogether, 3802 contacts have completed 21 days of monitoring as of November 26, 2022.

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